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Single-Cell Activity and Network Properties of Dorsal Raphe Nucleus Serotonin Neurons during Emotionally Salient Behaviors
The serotonin system modulates a wide variety of emotional behaviors and states, including reward processing, anxiety, and social …
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Single-Cell Activity and Network Properties of Dorsal Raphe Nucleus Serotonin Neurons during Emotionally Salient Behaviors
Blind demixing methods for recovering dense neuronal morphology from barcode imaging data
Cellular barcoding methods offer the exciting possibility of ‘infinite-pseudocolor’ anatomical reconstruction—i.e., assigning each …
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Blind demixing methods for recovering dense neuronal morphology from barcode imaging data
Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity
We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from ∼250 × 140 × 90 μm3 of electron microscopic …
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Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity
EASE: EM-Assisted Source Extraction from calcium imaging data
A pipeline for fusing CI and densely-reconstructed EM data is developed and an efficient iterative procedure for solving the resulting …
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EASE: EM-Assisted Source Extraction from calcium imaging data
Rapid mesoscale volumetric imaging of neural activity with synaptic resolution
Imaging neurons and neural circuits over large volumes at high speed and subcellular resolution is a difficult task. Incorporating a …
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Rapid mesoscale volumetric imaging of neural activity with synaptic resolution
CA1-projecting subiculum neurons facilitate object-place learning
Recent anatomical evidence suggests a functionally significant back-projection pathway from the subiculum to the CA1. Here we show that …
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A zero-inflated gamma model for deconvolved calcium imaging traces
Calcium imaging is a critical tool for measuring the activity of large neural populations. Much effort has been devoted to developing …
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A zero-inflated gamma model for deconvolved calcium imaging traces
Efficient and Accurate Extraction of in Vivo Calcium Signals from Microendoscopic Video Data
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Efficient and Accurate Extraction of in Vivo Calcium Signals from Microendoscopic Video Data
Anxiety Cells in a Hippocampal-Hypothalamic Circuit
The hippocampus is traditionally thought to transmit contextual information to limbic structures where it acquires valence. Using …
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Penalized matrix decomposition for denoising, compression, and improved demixing of functional imaging data
Calcium imaging has revolutionized systems neuroscience, providing the ability to image large neural populations with single-cell …
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